The Centre runs a series of monthly seminars by external speakers.
Thursday 15th January 2015, 1-2pm, Rose Room (Lower ground), LSHTM
Dr Jess Buxton, Centre for Cardiovascular Genetics, UCL
Title: Short telomeres and cardiometabolic disease risk: a causal link?
Telomeres are protective nucleoprotein structures that cap the ends of linear chromosomes. Vertebrate telomeres are composed of variable numbers of a tandem repeat sequence, (TTAGGG)n, bound to the shelterin protein complex. Telomere length is maintained by the action of telomerase in stem and germ cells, but in most somatic tissues, telomeres shorten with each cell division. In humans, mean leukocyte telomere length (LTL) is positively correlated with lifespan. Short LTL predicts the onset of several age-related diseases, including coronary artery disease (CAD) and type 2 diabetes. However, the mechanisms underlying the relationship between telomere shortening and cardiometabolic disease risk are currently unknown.
In this talk, I will present recent and ongoing work on the identification of novel genetic, epigenetic and other factors associated with telomere length, and outline potential pathways through which this biomarker of biological ageing may influence the onset of cardiometabolic and other age-related diseases.
Monday 9 February 2015, 1-2pm, Rose Room (Lower ground), LSHTM
Dr Damer Blake, Senior Lecturer in Molecular Parasitology, The Royal Veterinary College
Title: Parasite genetics for poultry: one less reason for the chicken to cross the road?
Monday 9 March 2015, 1-2pm,Rose Room (Lower ground), LSHTM
Dr Jordana Bell, Senior Lecturer / Head of Epigenomics Research Group, King’s College London
Tuesday 30th June 2015, Darwin LT, Darwin Building, UCL
BCGES Annual Conference
Listed separately are internal seminars at LSHTM.